Nlgn3 - neuroligin 3

Predicted to enable several functions, including cell adhesion molecule binding activity; neurexin family protein binding activity; and scaffold protein binding activity. Involved in several processes, including modulation of chemical synaptic transmission; regulation of neurotransmitter receptor activity; and regulation of synapse organization. Acts upstream of or within several processes, including oligodendrocyte differentiation; regulation of respiratory gaseous exchange by nervous system process; and visual learning. Predicted to be located in endocytic vesicle; excitatory synapse; and neuronal cell body. Predicted to be integral component of postsynaptic membrane. Predicted to be active in cell surface and synapse. Predicted to be integral component of postsynaptic specialization membrane. Predicted to colocalize with dendrite and inhibitory synapse. Is expressed in several structures, including central nervous system; eye; and heart. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in Asperger syndrome and autistic disorder. Orthologous to human NLGN3 (neuroligin 3). [provided by Alliance of Genome Resources, Apr 2022]