Lcat - lecithin cholesterol acyltransferase

Enables phosphatidylcholine-sterol O-acyltransferase activity and phospholipase A2 activity. Involved in several processes, including cholesterol metabolic process; response to copper ion; and response to glucocorticoid. Predicted to be part of high-density lipoprotein particle. Predicted to be active in extracellular space. Used to study end stage renal disease; familial hyperlipidemia; and myocardial infarction. Human ortholog(s) of this gene implicated in Norum disease and arteriosclerosis. Orthologous to human LCAT (lecithin-cholesterol acyltransferase). [provided by Alliance of Genome Resources, Apr 2022]