Mouse
Disc1 - disrupted in schizophrenia 1
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables molecular adaptor activity. Involved in several processes, including TOR signaling; nervous system development; and regulation of synapse maturation. Acts upstream of or within several processes, including mitochondrial calcium ion homeostasis; non-motile cilium assembly; and positive regulation of ubiquitin-dependent protein catabolic process. Located in microtubule organizing center; postsynaptic density; and synaptic vesicle. Is expressed in several structures, including brain; heart; liver; lung; and muscle tissue. Used to study endogenous depression and schizophrenia. Human ortholog(s) of this gene implicated in autism spectrum disorder (multiple); bipolar disorder; chronic fatigue syndrome; major depressive disorder; and psychotic disorder (multiple). Orthologous to human DISC1 (DISC1 scaffold protein). [provided by Alliance of Genome Resources, Apr 2022]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
4
13
217955 bp
92.53
15
12
Disc1 Genetics information (+)
GRCm39
Chr : -
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Sequence
Comparison
Al agent
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