Tox3 - TOX high mobility group box family member 3

Predicted to enable several functions, including chromatin DNA binding activity; protein homodimerization activity; and transcription coactivator activity. Predicted to be involved in calcium-mediated signaling; negative regulation of neuron apoptotic process; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; gut; and sensory organ. Orthologous to human TOX3 (TOX high mobility group box family member 3). [provided by Alliance of Genome Resources, Apr 2022]