Hoxb8 - homeo box B8

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of myeloid cell differentiation and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including dorsal spinal cord development; embryonic skeletal system morphogenesis; and grooming behavior. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human HOXB8 (homeobox B8). [provided by Alliance of Genome Resources, Apr 2022]