Enables histamine binding activity. Involved in several processes, including negative regulation of steroid biosynthetic process; positive regulation of nitric oxide biosynthetic process; and positive regulation of vasoconstriction. Predicted to be located in cytosol and plasma membrane. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Orthologous to human HRH1 (histamine receptor H1). [provided by Alliance of Genome Resources, Apr 2022]