Hdc - histidine decarboxylase

Enables several functions, including histidine decarboxylase activity; identical protein binding activity; and pyridoxal phosphate binding activity. Involved in histamine metabolic process and histidine metabolic process. Located in cytosol; dendrite; and neuronal cell body. Biomarker of rhinitis. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; asthma; and rhinitis. Orthologous to human HDC (histidine decarboxylase). [provided by Alliance of Genome Resources, Apr 2022]