Gstm1 - glutathione S-transferase mu 1

Enables several functions, including glutathione binding activity; glutathione transferase activity; and nickel cation binding activity. Involved in several processes, including response to ethanol; response to lead ion; and response to lithium ion. Located in cytosol and extracellular region. Part of protein-containing complex. Used to study cholestasis. Biomarker of hypertension and liver cirrhosis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human GSTM1 (glutathione S-transferase mu 1). [provided by Alliance of Genome Resources, Apr 2022]