Grm5 - glutamate metabotropic receptor 5

Enables A2A adenosine receptor binding activity; glutamate receptor activity; and protein tyrosine kinase binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; regulation of signal transduction; and trans-synaptic signaling. Located in astrocyte projection; dendrite; and postsynaptic density membrane. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane. Orthologous to human GRM5 (glutamate metabotropic receptor 5). [provided by Alliance of Genome Resources, Apr 2022]