Glud1 - glutamate dehydrogenase 1

Enables enzyme binding activity and glutamate dehydrogenase (NAD+) activity. Involved in cerebellum development; long-term memory; and response to aluminum ion. Located in mitochondrion. Biomarker of brain disease (multiple) and fascioliasis. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 6; hyperinsulinism; hypoglycemia; and late onset Parkinson's disease. Orthologous to several human genes including GLUD1 (glutamate dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]