Siglecg - sialic acid binding Ig-like lectin G

Predicted to enable SH2 domain binding activity; phosphatase binding activity; and sialic acid binding activity. Involved in several processes, including negative regulation of calcium-mediated signaling; negative regulation of inflammatory response to wounding; and regulation of B cell proliferation. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in thymus primordium. Orthologous to several human genes including SIGLEC10 (sialic acid binding Ig like lectin 10). [provided by Alliance of Genome Resources, Apr 2022]