Fkrp - fukutin related protein

Enables dystroglycan binding activity. Acts upstream of or within glycoprotein biosynthetic process and protein processing. Located in Golgi apparatus; extracellular space; and sarcolemma. Is expressed in brain. Used to study autosomal recessive limb-girdle muscular dystrophy type 2I; muscular dystrophy; muscular dystrophy-dystroglycanopathy; and muscular dystrophy-dystroglycanopathy type B5. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and muscular dystrophy (multiple). Orthologous to human FKRP (fukutin related protein). [provided by Alliance of Genome Resources, Apr 2022]