Fgb - fibrinogen beta chain

Predicted to enable chaperone binding activity; signaling receptor binding activity; and structural molecule activity. Predicted to contribute to cell adhesion molecule binding activity. Involved in cellular response to interleukin-1 and cellular response to leptin stimulus. Located in blood microparticle and cytoplasm. Biomarker of pancreatitis and pulmonary embolism. Human ortholog(s) of this gene implicated in cardiovascular system disease (multiple); congenital afibrinogenemia; and end stage renal disease. Orthologous to human FGB (fibrinogen beta chain). [provided by Alliance of Genome Resources, Apr 2022]