Iqsec3 - IQ motif and Sec7 domain 3

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including actin cytoskeleton organization; activation of GTPase activity; and regulation of small GTPase mediated signal transduction. Located in inhibitory synapse; postsynaptic density; and postsynaptic membrane. Is active in GABA-ergic synapse; glycinergic synapse; and postsynaptic specialization of symmetric synapse. Is expressed in endocrine gland; nervous system; and testis. Orthologous to human IQSEC3 (IQ motif and Sec7 domain ArfGEF 3). [provided by Alliance of Genome Resources, Apr 2022]