Prickle2 - prickle planar cell polarity protein 2

Predicted to enable zinc ion binding activity. Acts upstream of or within several processes, including establishment or maintenance of epithelial cell apical/basal polarity; neuron projection development; and trophectodermal cell fate commitment. Located in several cellular components, including apicolateral plasma membrane; lateral plasma membrane; and nucleus. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; notochord; and primitive streak. Orthologous to human PRICKLE2 (prickle planar cell polarity protein 2). [provided by Alliance of Genome Resources, Apr 2022]