Epor - erythropoietin receptor

Enables erythropoietin receptor activity. Involved in several processes, including cellular response to kainic acid; negative regulation of cell death; and negative regulation of nitric oxide biosynthetic process. Located in cytoplasm and external side of plasma membrane. Used to study high grade glioma. Biomarker of several diseases, including brain ischemia; cholangiocarcinoma; end stage renal disease; eye disease (multiple); and hepatic encephalopathy. Human ortholog(s) of this gene implicated in anemia; familial erythrocytosis 1; high grade glioma; polycythemia; and systemic lupus erythematosus. Orthologous to human EPOR (erythropoietin receptor). [provided by Alliance of Genome Resources, Apr 2022]