Enables enzyme binding activity; identical protein binding activity; and phosphopyruvate hydratase activity. Involved in several processes, including glucose metabolic process; negative regulation of neuron death; and response to estradiol. Located in several cellular components, including growth cone; membrane raft; and synaptic membrane. Part of phosphopyruvate hydratase complex. Biomarker of Parkinsonism; toxic shock syndrome; and visual epilepsy. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human ENO2 (enolase 2). [provided by Alliance of Genome Resources, Apr 2022]