Nqo1 - NAD(P)H quinone dehydrogenase 1

Enables NAD(P)H dehydrogenase (quinone) activity and superoxide dismutase activity. Involved in several processes, including NADPH oxidation; regulation of apoptotic process; and response to ischemia. Located in cytosol; dendrite; and neuronal cell body. Used to study several diseases, including chronic kidney disease; colon cancer; hypertension; liver cirrhosis; and membranous glomerulonephritis. Biomarker of several diseases, including brain disease (multiple); chronic obstructive pulmonary disease; fatty liver disease (multiple); prostatitis; and ureteral obstruction. Human ortholog(s) of this gene implicated in several diseases, including asthma; hematologic cancer (multiple); lung disease (multiple); macular degeneration; and small cell carcinoma. Orthologous to human NQO1 (NAD(P)H quinone dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]