Cyp1a2 - cytochrome P450, family 1, subfamily a, polypeptide 2

Enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Involved in several processes, including cellular response to copper ion; response to estradiol; and response to lipopolysaccharide. Located in intracellular membrane-bounded organelle. Biomarker of mental depression. Human ortholog(s) of this gene implicated in breast cancer; chronic obstructive pulmonary disease; endometrial cancer; and porphyria cutanea tarda. Orthologous to human CYP1A2 (cytochrome P450 family 1 subfamily A member 2). [provided by Alliance of Genome Resources, Apr 2022]