Enables calmodulin-dependent protein kinase activity; nitric-oxide synthase binding activity; and transmembrane transporter binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; protein phosphorylation; and regulation of calcium ion transmembrane transport. Located in cytosol; nucleus; and perinuclear region of cytoplasm. Part of protein-containing complex. Used to study epilepsy. Orthologous to human CAMK2D (calcium/calmodulin dependent protein kinase II delta). [provided by Alliance of Genome Resources, Apr 2022]