Calca - calcitonin-related polypeptide alpha

Predicted to enable calcitonin receptor binding activity and identical protein binding activity. Involved in several processes, including cellular response to nerve growth factor stimulus; cellular response to tumor necrosis factor; and vasodilation. Located in several cellular components, including axon; extracellular space; and neuronal cell body. Used to study acute necrotizing pancreatitis; ischemia; and stomach disease. Biomarker of prediabetes syndrome and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in migraine and osteoporosis. Orthologous to human CALCA (calcitonin related polypeptide alpha). [provided by Alliance of Genome Resources, Apr 2022]