Cad - carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
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Enables several functions, including aspartate carbamoyltransferase activity; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; and dihydroorotase activity. Involved in several processes, including alpha-amino acid metabolic process; animal organ development; and pyrimidine-containing compound biosynthetic process. Located in cytosol; neuronal cell body; and terminal bouton. Part of protein-containing complex. Used to study hepatocellular carcinoma. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 50. Orthologous to human CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase). [provided by Alliance of Genome Resources, Apr 2022]