Avp - arginine vasopressin

Enables V1A vasopressin receptor binding activity; V1B vasopressin receptor binding activity; and neuropeptide hormone activity. Involved in several processes, including cellular cation homeostasis; mating; and regulation of secretion. Located in dendrite; extracellular space; and secretory granule. Used to study diabetes insipidus; hyperglycemia; portal hypertension; temporal lobe epilepsy; and type 1 diabetes mellitus. Biomarker of hypertension; neurohypophyseal diabetes insipidus; type 2 diabetes mellitus; and vascular dementia. Human ortholog(s) of this gene implicated in diabetes insipidus and neurohypophyseal diabetes insipidus. Orthologous to human AVP (arginine vasopressin). [provided by Alliance of Genome Resources, Apr 2022]