IFIT5 - Interferon Induced Protein With Tetratricopeptide Repeats 5
Alias:
P58
RI58
ISG58
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Sequence Homology
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Enables nucleic acid binding activity. Involved in defense response to virus; negative regulation of viral genome replication; and positive regulation of I-kappaB kinase/NF-kappaB signaling. Located in actin cytoskeleton; apical part of cell; and ruffle membrane. Colocalizes with IkappaB kinase complex. [provided by Alliance of Genome Resources, Apr 2022]