Spry1 - sprouty RTK signaling antagonist 1

Involved in negative regulation of cell differentiation and negative regulation of signal transduction. Acts upstream of or within several processes, including bud elongation involved in lung branching; kidney development; and negative regulation of signal transduction. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; branchial arch; embryo ectoderm; limb; and sensory organ. Orthologous to human SPRY1 (sprouty RTK signaling antagonist 1). [provided by Alliance of Genome Resources, Apr 2022]