Sigirr - single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
Alias:
TIR8
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Involved in acute-phase response; negative regulation of chemokine production; and negative regulation of cytokine-mediated signaling pathway. Predicted to be located in membrane. Is expressed in genitourinary system. Orthologous to human SIGIRR (single Ig and TIR domain containing). [provided by Alliance of Genome Resources, Apr 2022]