Grk1 - G protein-coupled receptor kinase 1

Predicted to enable rhodopsin kinase activity. Acts upstream of or within several processes, including photoreceptor cell morphogenesis; positive regulation of phosphorylation; and post-embryonic retina morphogenesis in camera-type eye. Located in photoreceptor outer segment. Is expressed in retina outer nuclear layer. Used to study Oguchi disease-2. Human ortholog(s) of this gene implicated in Oguchi disease-2 and night blindness. Orthologous to human GRK1 (G protein-coupled receptor kinase 1). [provided by Alliance of Genome Resources, Apr 2022]