Papss2 - 3'-phosphoadenosine 5'-phosphosulfate synthase 2

Enables adenylylsulfate kinase activity and sulfate adenylyltransferase (ATP) activity. Acts upstream of or within blood coagulation; bone development; and sulfate assimilation. Is expressed in several structures, including genitourinary system; heart; limb; sensory organ; and skeleton. Used to study spondyloepimetaphyseal dysplasia, Pakistani type. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Pakistani type. Orthologous to human PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate synthase 2). [provided by Alliance of Genome Resources, Apr 2022]