Pacsin2 - protein kinase C and casein kinase substrate in neurons 2

Enables cytoskeletal protein binding activity and lipid binding activity. Involved in cell projection morphogenesis; modulation of chemical synaptic transmission; and plasma membrane tubulation. Acts upstream of or within negative regulation of endocytosis. Located in caveola; cell-cell junction; and cytosol. Is extrinsic component of membrane. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; aorta; eye; genitourinary system; and thymus. Orthologous to human PACSIN2 (protein kinase C and casein kinase substrate in neurons 2). [provided by Alliance of Genome Resources, Apr 2022]