Nr2e3 - nuclear receptor subfamily 2, group E, member 3

Enables DNA-binding transcription factor activity. Acts upstream of or within several processes, including eye development; negative regulation of cell population proliferation; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in 1st branchial arch maxillary component; early conceptus; eye; and oocyte. Used to study enhanced S-cone syndrome. Human ortholog(s) of this gene implicated in enhanced S-cone syndrome and retinitis pigmentosa 37. Orthologous to human NR2E3 (nuclear receptor subfamily 2 group E member 3). [provided by Alliance of Genome Resources, Apr 2022]