Hax1 - HCLS1 associated X-1

Predicted to enable interleukin-1 binding activity; protein N-terminus binding activity; and protein domain specific binding activity. Predicted to be involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of actin cytoskeleton organization. Predicted to act upstream of or within cell surface receptor signaling pathway. Located in several cellular components, including actin cytoskeleton; lamellipodium; and sarcoplasmic reticulum. Is expressed in coelomic epithelium of testis; ovary; and testis mesenchyme. Human ortholog(s) of this gene implicated in severe congenital neutropenia 3. Orthologous to human HAX1 (HCLS1 associated protein X-1). [provided by Alliance of Genome Resources, Apr 2022]