Gtf2h2 - general transcription factor II H, polypeptide 2

Predicted to enable RNA polymerase II general transcription initiation factor activity and protein N-terminus binding activity. Predicted to be involved in nucleotide-excision repair and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within DNA repair. Predicted to be located in nuclear speck. Predicted to be part of core TFIIH complex portion of holo TFIIH complex and transcription factor TFIID complex. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; integumental system; and nervous system. Orthologous to several human genes including GTF2H2C (GTF2H2 family member C). [provided by Alliance of Genome Resources, Apr 2022]