Dand5 - DAN domain family member 5, BMP antagonist

Enables morphogen activity. Involved in determination of left/right asymmetry in lateral mesoderm; heart development; and negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Acts upstream of or within determination of left/right symmetry and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be active in extracellular space. Is expressed in embryo; gut; node; and primitive streak. Orthologous to human DAND5 (DAN domain BMP antagonist family member 5). [provided by Alliance of Genome Resources, Apr 2022]