Klf6 - Kruppel-like factor 6

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of connective tissue replacement. Acts upstream of or within cytokine-mediated signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; genitourinary system; and peripheral nervous system. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human KLF6 (Kruppel like factor 6). [provided by Alliance of Genome Resources, Apr 2022]