Capn10 - calpain 10

Predicted to enable SNARE binding activity; calcium-dependent cysteine-type endopeptidase activity; and cytoskeletal protein binding activity. Involved in several processes, including actin cytoskeleton reorganization; positive regulation of transport; and type B pancreatic cell apoptotic process. Acts upstream of or within positive regulation of type B pancreatic cell apoptotic process. Predicted to be located in several cellular components, including cell cortex; cytosol; and mitochondrion. Predicted to be active in cytoplasm. Is expressed in dorsal root ganglion and renal calyx. Human ortholog(s) of this gene implicated in obesity; pancreatic cancer; polycystic ovary syndrome; and type 2 diabetes mellitus. Orthologous to human CAPN10 (calpain 10). [provided by Alliance of Genome Resources, Apr 2022]