Ash2l - ASH2 like histone lysine methyltransferase complex subunit

Predicted to enable beta-catenin binding activity and transcription cis-regulatory region binding activity. Predicted to contribute to histone methyltransferase activity (H3-K4 specific). Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in euchromatin. Part of MLL1 complex. Is expressed in several structures, including brain; branchial arch; genitourinary system; gut gland; and respiratory system. Orthologous to human ASH2L (ASH2 like, histone lysine methyltransferase complex subunit). [provided by Alliance of Genome Resources, Apr 2022]