Arih1 - ariadne RBR E3 ubiquitin protein ligase 1

Predicted to enable enzyme binding activity; ubiquitin protein ligase activity; and zinc ion binding activity. Acts upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be located in Lewy body and nuclear body. Predicted to be part of Cul3-RING ubiquitin ligase complex; Cul4A-RING E3 ubiquitin ligase complex; and SCF ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Is expressed in hippocampus. Orthologous to human ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1). [provided by Alliance of Genome Resources, Apr 2022]