Agr2 - anterior gradient 2

Predicted to enable dystroglycan binding activity; epidermal growth factor receptor binding activity; and identical protein binding activity. Involved in digestive tract morphogenesis; mucus secretion; and positive regulation of developmental growth. Acts upstream of or within lung goblet cell differentiation. Located in endoplasmic reticulum. Is expressed in several structures, including eye; genitourinary system; gut; liver; and lung. Orthologous to human AGR2 (anterior gradient 2, protein disulphide isomerase family member). [provided by Alliance of Genome Resources, Apr 2022]