Ptprq - protein tyrosine phosphatase, receptor type, Q

Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within several processes, including detection of mechanical stimulus involved in sensory perception of sound; hematopoietic progenitor cell differentiation; and vestibular receptor cell morphogenesis. Located in stereocilium bundle. Is expressed in cochlea; crista ampullaris; inner ear vestibular component; macula of utricle; and saccule. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 73 and autosomal recessive nonsyndromic deafness 84A. Orthologous to human PTPRQ (protein tyrosine phosphatase receptor type Q). [provided by Alliance of Genome Resources, Apr 2022]