Fancb - Fanconi anemia, complementation group B

Acts upstream of or within several processes, including cellular response to camptothecin; regulation of double-strand break repair via homologous recombination; and replication-born double-strand break repair via sister chromatid exchange. Predicted to be located in nucleus. Predicted to be part of Fanconi anaemia nuclear complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group B and head and neck squamous cell carcinoma. Orthologous to human FANCB (FA complementation group B). [provided by Alliance of Genome Resources, Apr 2022]