Leo1 - Leo1, Paf1/RNA polymerase II complex component
Alias:
Gm185
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Sequence Homology
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Predicted to enable RNA polymerase II C-terminal domain phosphoserine binding activity. Involved in endodermal cell fate commitment and stem cell population maintenance. Predicted to be located in centrosome; fibrillar center; and nucleoplasm. Predicted to be part of Cdc73/Paf1 complex. Predicted to be active in nucleus. Is expressed in brain; gonad; heart; and medial-nasal process mesenchyme. Orthologous to human LEO1 (LEO1 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Apr 2022]