Enables protein binding activity involved in heterotypic cell-cell adhesion. Acts upstream of or within clustering of voltage-gated sodium channels; heterotypic cell-cell adhesion; and microvillus organization. Located in extracellular space and plasma membrane. Is expressed in several structures, including genitourinary system; heart; lung; skeletal muscle; and spleen. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human GLDN (gliomedin). [provided by Alliance of Genome Resources, Apr 2022]