Chmp1a - charged multivesicular body protein 1A

Predicted to enable protein domain specific binding activity and protein homodimerization activity. Predicted to be involved in several processes, including midbody abscission; mitotic sister chromatid segregation; and regulation of cell cycle process. Predicted to be located in early endosome; microtubule organizing center; and nuclear lumen. Predicted to be part of ESCRT III complex. Predicted to be active in multivesicular body. Is expressed in 4th ventricle choroid plexus; 4th ventricle choroid plexus epithelium; cerebellum; cerebellum Purkinje cell layer; and cortical plate. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 8. Orthologous to human CHMP1A (charged multivesicular body protein 1A). [provided by Alliance of Genome Resources, Apr 2022]