Mouse
Aars1 - alanyl-tRNA synthetase
Alias:
sti
Aars
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Protein Interaction
Related Models
References
Enables Ser-tRNA(Ala) hydrolase activity; alanine-tRNA ligase activity; and translation regulator activity. Involved in alanyl-tRNA aminoacylation; regulation of cytoplasmic translational fidelity; and tRNA modification. Acts upstream of or within cerebellar Purkinje cell layer development; negative regulation of neuron apoptotic process; and neuromuscular process controlling balance. Predicted to be located in cytoplasm. Predicted to be active in mitochondrion. Is expressed in several structures, including adrenal gland; alimentary system; nervous system; respiratory system; and urinary system. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2N and developmental and epileptic encephalopathy 29. Orthologous to human AARS1 (alanyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Models
Reference
3
21
24457 bp
106.91
4
16
Aars1 Genetics information (+)
GRCm39
Chr : -
Sequence Homology
Selected Gene:
Mouse:Aars1
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Expression
Alphabetical
Cell-specific RNA expression
Organ
Expression
Alphabetical
Protein Interaction
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Models
Type
Name
MGI
Strain of Origin
Publications
No data available
References
Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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