Tpte - transmembrane phosphatase with tensin homology

Predicted to enable phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity and protein tyrosine phosphatase activity. Predicted to be involved in several processes, including dephosphorylation; phosphatidylinositol 3-kinase signaling; and regulation of protein kinase B signaling. Predicted to be located in Golgi apparatus and endoplasmic reticulum membrane. Predicted to be active in several cellular components, including cytosol; nucleus; and plasma membrane. Is expressed in brain; eye; future spinal cord; surface ectoderm; and testis. Orthologous to several human genes including TPTE2 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2). [provided by Alliance of Genome Resources, Apr 2022]