Dchs1 - dachsous cadherin related 1

Predicted to enable cadherin binding activity and calcium ion binding activity. Involved in several processes, including cell migration; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and hippo signaling. Acts upstream of or within several processes, including animal organ development; condensed mesenchymal cell proliferation; and post-anal tail morphogenesis. Located in apical part of cell. Is expressed in several structures, including alimentary system; central nervous system; heart; hemolymphoid system gland; and lung. Used to study mitral valve prolapse. Human ortholog(s) of this gene implicated in Van Maldergem syndrome 1 and mitral valve prolapse. Orthologous to human DCHS1 (dachsous cadherin-related 1). [provided by Alliance of Genome Resources, Apr 2022]