Lrrk1 - leucine-rich repeat kinase 1

Predicted to enable identical protein binding activity and protein kinase activity. Acts upstream of or within several processes, including bone resorption; osteoclast development; and regulation of peptidyl-tyrosine phosphorylation. Predicted to be located in cytosol and mitochondrion. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Used to study osteopetrosis. Orthologous to human LRRK1 (leucine rich repeat kinase 1). [provided by Alliance of Genome Resources, Apr 2022]