Enables inositol-1,4,5-trisphosphate 3-kinase activity. Predicted to be involved in inositol phosphate biosynthetic process and phosphatidylinositol phosphate biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in nuclear speck. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including blastocyst and early embryo. Orthologous to human ITPKC (inositol-trisphosphate 3-kinase C). [provided by Alliance of Genome Resources, Apr 2022]