Ap5z1 - adaptor-related protein complex 5, zeta 1 subunit

Predicted to be involved in double-strand break repair via homologous recombination and endosomal transport. Predicted to act upstream of or within DNA repair and protein transport. Predicted to be located in cytoplasm and nuclear speck. Predicted to be part of AP-5 adaptor complex. Used to study hereditary spastic paraplegia 48. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia and hereditary spastic paraplegia 48. Orthologous to human AP5Z1 (adaptor related protein complex 5 subunit zeta 1). [provided by Alliance of Genome Resources, Apr 2022]