Uba6 - ubiquitin-like modifier activating enzyme 6

Enables FAT10 activating enzyme activity and ubiquitin activating enzyme activity. Involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Acts upstream of or within several processes, including dendritic spine development; learning; and limbic system development. Predicted to be active in cytoplasm and nucleus. Is expressed in gonad. Orthologous to human UBA6 (ubiquitin like modifier activating enzyme 6). [provided by Alliance of Genome Resources, Apr 2022]